digitalMLPA Assays
SALSA® digitalMLPA is a revolution in copy number variation (CNV)
detection. digitalMLPA builds off the robust MLPA technology and employs the power of Illumina next generation sequencing platforms for data generation. This new technology offers an impressive scaleup in CNV detection with the inclusion of up to 1000 probes in a single reaction on just 20 ng of DNA. digitalMLPA advantages include:
- Reliable: proven copy number detection technology
- Robust: only 20 ng of sample DNA needed, uniform coverage
- Quality control: control probes included in each reaction
- Simple: easy hands-on steps and no library quantification needed
- Cost-effective: up to 1000 probes in one reaction
- Sample certainty: SNV probes present to distinguish samples
- Easy analysis: user-friendly analysis with free Coffalyser digital MLPA
The technology uses hands-on steps that are very similar to those in MLPA, with the main difference being that data generation is done on an Illumina NGS platform. digitalMLPA products can be loaded directly onto the sequencer, without needing clean up or library quantification. Data analysis is performed using free MRC Holland-developed software: Coffalyser
