Custom Oligonucleotides (Black Hole Quencher dyes, Fluorophores, Nucleotides, and more) are used for molecular diagnostics and research and include
Black Hole Quencher Probes and Assays
Black Hole Quencher (BHQ®)-labeled probes are ideal for qualitative and quantitative PCR (qPCR) experiments such as single and multiplex gene expression, copy number variation (CNV), SNP genotyping and presence/absence. BHQ probes are designed using Black Hole Quencher dyes with broad absorption spectra.
Molecular Beacons and Scorpions® Primers
These qPCR primers and probes are available as alternatives to MGB probes when greater discrimination and faster reaction times are desired. They can be ordered with a variety of fluorophores. Choose from up to 15 different fluorophores and corresponding Black Hole Quencher dye.
Calibration and Reference Dyes
Instrument Calibration Dyes improve signal deconvolution in real-time qPCR thermal cyclers that require spectral calibration. They enable the instrument to store the fluorescent profile of each dye and control for crosstalk. Passive Reference Dye - SuperROX® - is a specially formulated version of the ROX (carboxy-X-rhodamine) fluorophore that provides a more uniform passive reference signal compared to standard ROX dyes. This dye is commonly used as passive reference to normalize signal variations not related to the PCR amplification.
Whether you need research-grade, product design verification and validation, or GMP-compliant oligos, we manufacture to the highest standards in a cost-effective manner and with rapid turnaround times to enable your timely project completion.