Electrofusion Systems – Hybrimune™ Hybridoma (BTX)

The Hybrimune™ Hybridoma Production  System is an advanced electrofusion system for fast, efficient cell fusion in hybridoma production, hybrid cell formation or dendritic-tumor cell fusions

The Hybrimune system includes an innovative fusion chamber design, proprietary BTXpress® Cytofusion medium and sophisticated, tri-phasic electric field pulses that quickly position cells and disrupt cell membranes for maximum cell fusion efficiency with short cycle-times and minimal heating or turbulence for excellent cell viability. In addition, Hybrimune delivers a cell alignment waveform which is a patented sequence that enhances hybridoma yield. The Hybrimune system consists of a user-friendly, programmable waveform generator controlled through the User-Interface Application Software running on a Windows-based computer system (not included). The fusion chamber uses coaxial electrodes designed for optimal electric field stimulation, independent of bath height. In this way, pulse parameters defined with the low volume optimization chamber are directly applicable for the large volume production chamber. The optimization chamber includes a transparent bottom for microscope viewing during the process optimization.