Selector resins are based on high-affinity single-domain antibodies (sdAb) which are covalently immobilized on 4% cross-linked agarose beads
The oriented and selective attachment via a flexible linker guarantees a high accessibility of the sdAbs and largely eliminates batch-to-batch variations. Due to the single-chain nature of sdAbs and their covalent attachment, no "leakage" of light and heavy chains from IgGs is observed during elution with SDS sample buffer. Key benefits of selector resins include:
- High capacity
- Minimal unspecific binding
- No co-elution of heavy and light chain; and
- Broad buffer compatibility for high flexibility.
See attached flyer for the full range of the Selector Portfolio. Please
contact us for more information.
