Probemixes – SALSA digitalMLPA / SALSA MLPA / SALSA Melt (MRC Holland)

Probemixes – SALSA digitalMLPA / SALSA MLPA / SALSA Melt (MRC Holland)

MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease
**NEW** SALSA® digitalMLPA
SALSA digitalMLPA is a revolution in copy number variation (CNV) detection. digitalMLPA builds off the robust MLPA technology and employs the power of Illumina next generation sequencing platforms for data generation. This new technology offers an impressive scaleup in CNV detection with the inclusion of up to 1000 probes in a single reaction on just 20 ng of DNA. The first digitalMLPA application on the market is D001 Hereditary Cancer Panel 1. The technology uses hands-on steps that are very similar to those in conventional MLPA, with the main difference being that data generation is done on an Illumina NGS platform. digitalMLPA products can be loaded directly onto the sequencer, without needing clean up or library quantification. Data analysis is performed using free MRC Holland-developed software: Coffalyser digitalMLPA.
SALSA® MLPA®
MLPA is the gold standard for the quantification of copy numbers. Up to 60 different genomic DNA sequences can be quantified simultaneously. MLPA products are used worldwide to study hereditary disorders, tumour profiling and methylation status in diagnostic and research. With over 400 targeted assays on the market, there is always one that meets your needs.
SALSA® Melt Assays
SALSA Melt Assays are based on high-resolution melt curve analysis, and are a fast and affordable way to identify specific allelic variants that may be associated with disease. At present MRC Holland offer one Melt Assay: SALSA MC002 SMA Newborn Screen. This assay can reliably identify 95-98% of SMA patients.
Coffalyser.Net: MLPA® analysis software
Coffalyser.Net is free MLPA analysis software made and supported by MRC Holland. Coffalyser.Net can directly import raw data files and performs advanced quality checks to increase the robustness of your MLPA results. Analysis sheets for each product can be retrieved directly from MRC Holland servers, ensuring you always have access to the latest versions.
Please contact Fisher Biotec for more information or free call 1800 066 077.
BROWSE WITH ASSAY FINDERLINKS TO MORE INFORMATIONGENERAL MLPA INFORMATIONENQUIRE ABOUT THIS PRODUCT