Electrofusion Systems

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Manufacturer: BTX Harvard Apparatus

Description:

The ECM® 2001 is a multipurpose Electro Cell Manipulation generator capable of producing a proprietary AC waveform for benign dielectrophoretic alignment of cells, and a square DC waveform for cell fusion. Applications include Cell Fusion; Nuclear Transfer; Embryo Manipulation; Hybridoma Production; Mammalian Cell Transfection; Plant Protoplast Fusion and Stem Cell Production.

Microsecond switch-over time from AC to DC allows for highly efficient fusion. After fusion, the AC pulse reapplication maintains compression of the cells following the DC pulse for the rounding off process; resulting in a higher number of hybrids. The 1 MHz AC pulse aligns cells together in “real time”, saving time (seconds vs. hours) in comparison to PEG methods. Blastomeres and Oocytes can also be aligned to the correct position for better fusion accuracy during nuclear transfer and embryo manipulation.

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